DMCA. Copyrighted Work that you can Claim.
Base have 37 000 books.
Search: 


📙 Novel Therapeutic Targets for Antiarrhythmic Drugs by George Edward Billman — download pdf


Profiles potential treatment approaches for cardiac arrhythmias

Cardiac arrhythmias of ventricular origin are responsible for the deaths of nearly half a million Americans each year while atrial fibrillation accounts for about 2.3 million cases per year, a rate that is projected to increase 2.5 fold over the next half century. Effectively managing these cardiac rhythm disorders remains a major challenge for both caregivers and the pharmaceutical industry. Filling a gap in the current literature, Novel Therapeutic Targets for Antiarrhythmic Drugs presents the latest treatments for cardiac arrhythmias alongside comprehensive presentations of basic cardiac physiology and pharmacology.

Written by leading experts in their research areas, this invaluable resource offers both practitioners and researchers a one-stop guide that brings together previously dispersed information. The text consists of four sections:

  • Section One comprehensively reviews basic cardiac electrophysiology, the mechanisms responsible for arrhythmias in the setting of ischemia, and basic pharmacology of antiarrhythmic drugs.

  • Section Two addresses safety pharmacology, including the concept of "repolarization reserve," safety challenges, and regulatory issues for the development of novel antiarrhythmic drugs.

  • Section Three describes several novel pharmacological targets for antiarrhythmic drugs, including both ion channel and non-ion channel targets.

  • Section Four describes promising non-pharmacological antiarrhythmic interventions including selective cardiac neural disruption or nerve stimulation, aerobic exercise training, and diet (omega-3 fatty acids).

Offering an unparalleled look at the current state and future direction of cardiac arrhythmia treatment, Novel Therapeutic Targets for Antiarrhythmic Drugs provides an important resource to advanced students, working researchers, and busy professionals alike.

About book:

About file:

  • File size: 4 649 847
  • Format: djvu


Security code:
Download button

Similar books results


Molecular Cancer Therapeutics: Strategies for Drug Discovery and Development
Molecular Cancer Therapeutics: Strategies for Drug Discovery and Development pdf free by

Molecular Cancer Therapeutics covers state-of-the-art strategies to identify and develop cancer drug target molecules and lead inhibitors for clinical testing. It provides a thorough treatment of drug target discovery, validation, and development. The int...

Arthritis Research: Methods and Protocols
Arthritis Research: Methods and Protocols (Volume 1) free epub by Andrew P. Cope

Arthritis Research: Methods and Protocols is a compendium of data pertinent to the methods and protocols that have contributed to recent advances in molecular medicine in general, but to the molecular basis of rheumatic disease in particular. These volume...

Therapeutic Groups for Obese Women: A Group Leader's Handbook
Therapeutic Groups for Obese Women: A Group Leader's Handbook pdf free by Julia Buckroyd, Sharon Rother

Based on a five-year research project, Therapeutic Groups for Obese Women introduces an innovative approach to overcoming the growing socio-economic burden of morbidity and mortality resulting from emotionally-driven female obesity. Julia Buckroyd and S...

Neuropeptide Systems as Targets for Parasite and Pest Control
Neuropeptide Systems as Targets for Parasite and Pest Control download pdf by Debra Woods, Cheryl Butler, Tracey Williams (auth.), Timothy G. Geary PhD, Aaron G. Maule PhD (eds.)

The need to continually discover new agents for the control or treatment of invertebrate pests and pathogens is undeniable. Agriculture, both animal and plant, succeeds only to the extent that arthropod and helminth consumers, vectors and pathogens can be...

Arachidonate Remodeling and Inflammation
Arachidonate Remodeling and Inflammation download pdf by Alfred N. Fonteh (auth.), Alfred N. Fonteh, Robert L. Wykle (eds.)

Arachidonic acid (AA) and other 20 or 22-carbon polyunsaturated fatty acids (PUFAs) are precursors of lipid mediators of inflammation known as eicosanoids. These mediators are critical in disease processes and in regulating normal cell function. Remodelin...

Novel Delivery Systems for Transdermal and Intradermal Drug Delivery
Novel Delivery Systems for Transdermal and Intradermal Drug Delivery free pdf by Donnelly, Ryan F.; Singh, Thakur Raghu Raj

This research book covers the major aspects relating to the use of novel delivery systems in enhancing both transdermal and intradermal drug delivery. It provides a review of transdermal and intradermal drug delivery, including the history of the field an...

Drug Delivery Systems
Drug Delivery Systems free pdf by Ranade V.V., Hollinger M.A.

The demand for innovative drug delivery systems continues to grow, and this growth continues to drive new developments. This new edition covers the latest developments in both industry and academia. New in this edition: a chapter focusing on novel technol...

Drug Delivery and Targeting: For Pharmacists and Pharmaceutical Scientists
Drug Delivery and Targeting: For Pharmacists and Pharmaceutical Scientists free pdf by Anya M. Hillery, Andrew W. Lloyd, James Swarbrick

Saint Louis Univ., Madrid Campus, Spain. Provides a comprehensive introduction to the principles of advanced drug delivery and targeting, their current applications and potential future developments. Includes learning objectives, color illustrations and t...

Nucleic Acid Targeted Drug Design
Nucleic Acid Targeted Drug Design epub download by Catherin Propst

Northwestern University, Evanston, Illinois. State-of-the-art text on the use of nucleic acids as targets for molecular design of drugs. For researchers in drug design. Highlights methods and applications. Companion to Computer-Aided Drug Design, by Perun...

An Elementary Treatise on Curve Tracing
An Elementary Treatise on Curve Tracing pdf free by Percival Frost

Accessible treatment explores parabolic curves at an infinite distance, curves in the neighborhood of the origin, forms of branches whose tangents at the origin are the coordinate axes, more...

An EAI solution using WebSphere Business Integration

An Economic History of the American Steel Industry
An Economic History of the American Steel Industry free download by Robert P. Rogers

This book provides a basic outline of the history of the American steel industry, a sector of the economy that has been an important part of the industrial system. The book starts with the 1830's, when the American iron and steel industry resembled the tr...

An den Grenzen menschlichen Wissens

An Elementary Guide To Reliability
An Elementary Guide To Reliability free pdf by G. Dummer, R. WINTON, Mike Tooley BA; Advanced Technological and Higher National Certificates Kingston University

This classic text has now been completely revised and updated, making it an ideal introductory course in reliability for a wide range of engineering qualifications, including City & Guilds 8030 and HNC/Ds. A new chapter focuses on the role of the micropro...

An elementary introduction to mathematical finance
An elementary introduction to mathematical finance download pdf by Ross S.M.

This textbook on the basics of option pricing is accessible to readers with limited mathematical training. It is for both professional traders and undergraduates studying the basics of finance. Assuming no prior knowledge of probability, Sheldon M. Ross o...

  An economic analysis of democracy
An economic analysis of democracy free pdf by Randall G. Holcombe

Democratic decisions determine the al­location of resources through the public sector. Holcombe uses the median voter model as a base, but goes on to develop a more general multidimensional model of democratic decision making that incor­porates many theor...

An easy out : corporate America's addiction to outsourcing

An Elementary Survey of Celestial Mechanics
An Elementary Survey of Celestial Mechanics free download by Y. Ryabov, Physics, G. Yankovsky

An accessible exposition of gravitation theory and celestial mechanics, this classic volume was written by a distinguished Soviet astronomer. It explains with exceptional clarity the methods used by physicists in studying celestial phenomena, including pe...

An Efficient Energy Future. Prospects for Europe and North America